Current Research Studies

  • Principal Investigator:

    Alla Landa, PhD
    Why do some individuals continue to experience chronic symptoms of Lyme Disease, such as pain, fatigue, sensory hypersensitivity, and neurocognitive difficulties long after receiving treatment? Through the use of brain imaging (functional MRI) and specific biomarker testing, we hope to gain a better understanding as to why patients develop this persistent, debilitating pain. Based on prior research, we suspect that Lyme disease may change the pattern of an individual's brain activation, making him or her more sensitive to pain than a healthy person. If we can identify the hyper-activated...
  • Principal Investigator:

    Brian A Fallon, MD
    Why do some patients recover quickly after Lyme disease while others develop chronic symptoms? To answer this question, we need to enroll patients at different stages of illness -- early at the initial infection when it affects the skin, joints, nervous system or heart, and later as well to see who has recovered and who has persistent symptoms. Some have only a mild illness associated with the rash. Others are quite ill and may not be sure when they were infected. We follow each patient carefully over 2 years. During this interval, we collect blood and conduct objective assessments of...
  • Principal Investigator:

    Alla Landa, PhD
    We are recruiting healthy volunteers to participate in our diagnostic brain imaging study. This new study aims to investigate individuals experiencing persistent pain that was triggered by Lyme Disease. By utilizing brain imaging (functional MRI), we hope to gain a better understanding of why patients have ongoing problems with persistent pain, fatigue, and sensory sensitivity even after antibiotic treatment. We suspect that Lyme disease may change the pattern of an individual's brain activation, making him or her more sensitive to pain than a healthy person. To test this hypothesis, we will...