Current Research Studies

  • Clinical Research Registry for Lyme and Other Tick-borne Diseases

    Principal Investigator:

    Brian A Fallon, MD, MPH
    This patient case registry for Lyme and other Tick-borne Diseases is a component of the Clinical Trials Network that was launched in 2021 by a grant from the Steven and Alexandra Cohen Foundation. The registry will gather general information such as demographics, medical history, and current functional status. This information will help researchers to identify individuals who may meet criteria for current or future research studies. It will also help us to share news and updates about ongoing clinical research. Individuals in the registry may receive notifications from the Columbia research...

  • Transcranial Direct Current Stimulation (tDCS): A New Treatment of Brain Fog in Previously Treated Lyme Disease Patients

    Principal Investigator:

    Brian A Fallon, MD, MPH
    Have you been treated for Lyme Disease but continue to have brain fog or other cognitive problems? This research study will assess a non-medication non-invasive intervention to improve cognitive functioning in people with persistent cognitive problems despite prior antibiotic treatment for Lyme Disease. Participants will complete this 4 week intervention at home, with up to 4 in person visits to our research center in New York City before and after the treatment period. Mood and other clinical rating questionnaires will be completed at several time points online. The intervention will consist...

  • Vagus Nerve Stimulation: A New Treatment Study for Previously Treated Lyme Disease Patients with Persistent Symptoms

    Principal Investigator:

    Brian A Fallon, MD, MPH
    Are you suffering from persistent symptoms that began after you were diagnosed and treated with antibiotics for Lyme Disease? This new research study aims to test a new form of treatment for people with persistent symptoms despite antibiotic treatment for Lyme disease. This treatment involves stimulating a nerve on the surface of your ear. This is called transcutaneous (through the skin) auricular (ear) vagus nerve stimulation (taVNS). Published studies report that vagus nerve stimulation (VNS) can help to reduce pain, fatigue, depression, and inflammation; some studies suggest it can improve...