Current Research Studies
Principal InvestigatorBrian A. Fallon, MDWhy do some patients recover quickly after Lyme disease while others develop chronic symptoms? To answer this question, we need to enroll patients at different stages of illness -- early at the initial infection when it affects the skin, joints, nervous system or heart, and later as well to see who has recovered and who has persistent symptoms. Some have only a mild illness associated with the rash. Others are quite ill and may not be sure when they were infected. We follow each patient carefully over 2 years.
Principal InvestigatorBrian A. Fallon, MDThis long-term goal in this study is to reduce the number of patients who develop symptoms of chronic Lyme disease (also known as Post-treatment Lyme Syndrome) by identifying better tests and by understanding the immunologic, rheumatologic, and neurologic impact of this illness over time. This can only be done by comparing those patients who recover fully to those who experience ongoing symptoms, as well as to healthy controls. While at the Center, we will collect blood and conduct very careful clinical assessments.
Principal InvestigatorBrian A. Fallon, MDThe CDC estimates that 10-20% of patients with Lyme disease will go on to have chronic symptoms despite having had appropriate treatment, a condition known as Post-Treatment Lyme Disease Syndrome (PTLDS). While there is currently no known cure, various therapies are being investigated.